Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a7f82940e47ba7a1188f8e2ffca55e0f |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-525 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-96486 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-24086 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6489 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6424 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-37 |
filingDate |
2006-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_041fdd520cce2e2d7cea578280c521ca http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f368362a013d166afa1b4acd68639889 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_54058a58160194d299f4f17fbaf65227 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cbddf5b0bac0f5d7d777ff76f236188a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0feac86dcfcc2e4224ddfee28e7d3f4a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8eb2256dc5693b3156253413b1782c7a |
publicationDate |
2007-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2007141603-A1 |
titleOfInvention |
Mammalian TNF-alpha convertases |
abstract |
The present invention provides isolated human and bovine TNF-α convertases, nucleic acids and; recombinant vectors encoding the same, host cells comprising the nucleic acids and vectors, and methods for making the convertases using the host cells. This invention further provides antibodies and antigen binding fragments thereof which specifically bind to the convertases and are useful for treating medical conditions caused or mediated by TNF-α. Also provided are screening methods for identifying specific inhibitors of mammalian TNF-α convertases, and for identifying nucleic acids encoding such convertases. |
priorityDate |
1996-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |