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filingDate 2006-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2007-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2007134695-A1
titleOfInvention Dengue virus detection measured by immunocytometry in a dendritic cell surrogate
abstract The invention concerns a method for diagnosing dengue invention early after dengue virus infection. The method comprises binding dengue virus contained in sera from infected patients with dentritic cell-specific intracellular adhesion molecule (ICAM) 3-grabbing nonintegrin (DC-SIGN) or liver/lymph node-specific intracellular adhesion molecule (ICAM) 3-grabbing nonintegrin (L-SIGN). DC-SIGN or L-SIGN can be expressed in transfected B cells or adhered to other surfaces. Measurement of binding is by immunocytometry, microscopy or other antibody based methods.
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