| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42e94091a4fc81b8d0237117707cc7ee |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2603-74 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-47 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-84
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-403
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-198 |
| filingDate |
2007-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_27503fc890517f1395096dd5660d6a84
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d58e9696302abcdba7f3a50378252fa4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_743549ef0381adb01ab22d4e2f5c8ff4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12664253b9ca1b8fd38706605c460f0e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81b4e2d081092cece87c2dd3155888a5 |
| publicationDate |
2007-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2007123579-A1 |
| titleOfInvention |
Process for preparing a dipeptidyl peptidase iv inhibitor and intermediates employed therein |
| abstract |
A process is provided for preparing a dipeptidyl peptidase IV inhibitor of the structure n n nis treated with TFAA in isopropyl acetate to protect the tertiary hydroxyl group as a trifluoroacetate group to form 4 n n nwhich is converted to acid chloride compound 5 n n n(which is a novel compound) using Vilsmeier reagent or other chloro reagent and coupled with compound 6 in a heterogeneous mixture of ethyl acetate and aqueous bicarbonate to give compound 7 n nThe N,O-bis(trifluoroacetyl) groups of compound 7 are deprotected to give free base compound 10. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11253508-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11400072-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10772865-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10555929-B2 |
| priorityDate |
2004-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |