| abstract |
The present invention discloses methods of labeling Fc portions of antibodies, or fusion proteins incorporating Fc portions of antibodies, so that they can be used in immunostaining or immunolabeling procedures. A wide variety of labels can be used. A linker can be used between the label and the protein to be labeled, allowing for flexibility in labeling. A large variety of coupling reactions can be used to generate the labeled protein molecule, The protein molecule to be labeled can be part of a larger fusion protein. The labeled protein molecules can be used in immunostaining and immunolabeling procedures but also in in vivo applications for therapy and diagnostic imaging. |