Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7f3109befbff2bcd31b2339d5610e0ef http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2b3eacea7f5563b3f022ef608bf955aa http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_870832d1e91e735015b1f7a4395b6084 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3310f8e3f1d35064c9d25dd04f1ccb72 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-567 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate |
2003-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc8a50e1c5b1d7244644662bfc6479d9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a8af6326337e14186c5de1e93826b9d3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a0cff38d0593e4e901babc30485ed98d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_87e3d1c0581792c3e5a06f98c329fca6 |
publicationDate |
2007-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2007118913-A1 |
titleOfInvention |
Diagnostic and therapeutic use of steroidogenic acute regulatory protein for neurodegenerative diseases |
abstract |
The present invention discloses the differential expression of the steroidogenic acute regulatory protein (StAR) gene in specific brain regions of Alzheimer's disease patients. Based on this finding, this invention provides a method for diagnosing or prognosticating a neurodegenerative disease, in particular Alzheimer's disease, in a subject, or for determining whether a subject is at increased risk of developing such a disease. Furthermore, this invention provides therapeutic and prophylactic methods for treating or preventing Alzheimer's disease and related neurodegenerative disorders using the StAR gene and gene products. A method of screening for modulating agents of neurodegenerative diseases is also disclosed. |
priorityDate |
2002-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |