Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c00ed6834c2b5d9b9f44ed1a3daf130b |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-172 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6888 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate |
2006-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7bee4e36285ba96f11e808d33c6463dc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cbaee27405c1087b6cd174c8b2abb17d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ce0484dd2911c8134ed1081bb0baa45d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c50ca8808cb395802be527e801f6202 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_919c87db7d38be01e20ecc511fec7b09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be8b77d5bddaecc1b3b3a798d8aaf82e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_439ba5492abf5bb76b874abb99107684 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8cafb4064684d8d55a0e295bea949fe8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5db8ed1d5e7f010d0636768736e80b09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_074bcea65af19f3c6f64f2a7db5c3ac3 |
publicationDate |
2007-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2007118912-A1 |
titleOfInvention |
Bovine abcg2 gene missense mutations and uses thereof |
abstract |
A quantitative trait locus (QTL) affecting milk fat and protein concentration was localized to a 4cM confidence interval on chromosome 6 centered on the microsatellite BM143. The genes and sequence variation in this region were characterized, and common haplotypes spanning five polymorphic sites in the genes IBSP, SPP1, PKD2, and ABCG2 for two sires heterozygous for this QTL were localized. Expression of SPP1 and ABCG2 in the bovine mammary gland increased from parturition through lactation. SPP1 was sequenced, and all the coding exons of ABCG2 and PKD2 were sequenced for these two sires. The single nucleotide change capable of encoding a substitution of tyrosine-581 to serine (Y581S) in the ABCG2 transporter was the only polymorphism corresponding to the segregation status of all three heterozygous and 15 homozygous sires for the QTL in the Israeli and US Holstein populations. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2458788-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2458788-A |
priorityDate |
2005-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |