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filingDate 2006-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2007-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2007110674-A1
titleOfInvention Sono-active liposomes and lipid particles and use thereof as contrast agents and active-agent delivery systems
abstract The present invention is directed to a novel class of gas filled liposomal delivery system particles, and to methods of making these particles, including the production of gas filled liposomal delivery system particles via chemical reaction to produce gas bubbles inside the particles. The present invention also includes: gas filled liposomal delivery system particles containing one or more active agents; gas filled liposomal delivery system particles for visualization purposes, e.g., for visualization of structures of the body via ultrasound waves; gas filled liposomal delivery system particles for the targeted delivery of active agent to one or more areas of interest of the body; and, gas filled liposomal delivery system particles for the targeted delivery of active agent to one or more areas of interest of the body, where targeting specificity is enhanced by active targeting to direct the gas filled liposomal delivery system particles to a particular target.
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