Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d1d1b5eb8d4613e5b917c656d29fd775 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6853 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6844 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate |
2004-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a0fc27e9109db7edc2b14b475a84a4dc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ff6e2d142ea72d2bce7a9eb5c6fa76d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a548c0fe63e661f4354d9762f797fb44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bfc90d99d12ce91ae78a10cbdf54397d |
publicationDate |
2007-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2007105099-A1 |
titleOfInvention |
Nucleic acid amplification using non-standard bases |
abstract |
The present invention provides methods, kits and compositions for high fidelity nucleic acid amplification reactions of target nucleic acids such that specific amplification products that incorporate non-standard bases are produced. The amplification reactions can either be linear or exponential. In some embodiments, the fidelity of the amplification reaction is high enough such that a majority of the amplification products maintain non-standard bases at specific sites designated by the user after a specified number of amplification cycles. In some embodiments, the ratio of non-standard nucleoside triphosphates is greater than the amount of standard nucleoside triphosphates initially present in the reaction mixture. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009123216-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014035498-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10865431-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8426569-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011053782-A1 |
priorityDate |
2003-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |