| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1d350625286def8f8f8172a3d67dd0ca |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5047
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6897
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5008
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5014
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-502 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-567
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
| filingDate |
2006-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4165718aa95d5a179415790857cae63a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_690367a32a362f48732bd0982089f1ed
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2dc9e49a36b2decd6020ebebfc0e1d0f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_edf72224b4e8d89662ad4835b22fd83b |
| publicationDate |
2007-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2007087333-A1 |
| titleOfInvention |
Method to detect antigen-specific cytolytic activity |
| abstract |
The invention relates to a novel non-radioactive method to detect cytolytic activity that provides a measure of the existence and magnitude of an immune response against a particular antigen or immunogen. Provided is a method for detecting cytolytic activity of cells or a substance against a population of target cells, comprising the steps of providing target cells with a first nucleic acid sequence encoding a reporter molecule and a second nucleic acid sequence encoding an antigen of interest; co-culturing the target cells with a sample containing cells or a substance suspected of having cytolytic activity; and detecting the viability of target cells provided with the reporter molecule. Also provided are a kit and a nucleic acid for use in a method according to the invention. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11220718-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10539523-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9944997-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9834824-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10551371-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023103785-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10533985-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9803252-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109475874-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11604197-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11162148-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10690677-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10287640-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11346797-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11746328-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10167524-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-D941488-S
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113943751-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017087945-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10725023-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10519517-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11360072-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10620188-B2 |
| priorityDate |
2004-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |