| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69ece09bafee7e0c49d1f7951a3faa2c |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-30 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4756
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-71
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82B1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-475
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-74
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-71
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 |
| filingDate |
2006-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_03b121a222732348db66bc1a792c0cf2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7067ab73d82a46e22a5206dc77489b9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_37ce35913515028e49a5fe41c4d1a80c |
| publicationDate |
2007-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2007081994-A1 |
| titleOfInvention |
Chimeric Heteromultimer Adhesins |
| abstract |
Novel chimeric heteromultimer adhesins that bind the ligand of natural heteromultimeric receptors and uses therefor are disclosed. The chimeric molecules of the heteromultimer adhesins comprise an extracellular domain of a heteromultimeric receptor monomer and a multimerization domain for the stable interaction of the chimeric molecules in the adhesin. Specifically disclosed are heteromultimeric adhesins comprising the extracellular domains of ErbB2 and ErbB3 or ErbB2 and ErbB4. The chimeric ErbB heteromultimer adhesins of the present invention are useful as competitive antagonists or agonists of a neuregulin for the treatment of diseases such as various cancers. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8961966-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8895001-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10273304-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10184006-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8623592-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011123523-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011159513-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010266584-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009291085-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8691225-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011027291-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7846440-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9688761-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9518130-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9487588-B2 |
| priorityDate |
1996-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |