http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007077255-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fb5efd635e4caaa96abe3a235a7caca3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_292b0d28b8d6f542e51229df197a8de5 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-385 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-385 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 |
| filingDate | 2006-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62d091214d5e78df43dcf217e1b0fb05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_291d2b93444ec2c011743ade1132b31b |
| publicationDate | 2007-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2007077255-A1 |
| titleOfInvention | Isolation and characterization of a cDNA clone encoding one IgE-binding fragment of Penicillium brevicompactum |
| abstract | Pen b 26 was isolated as an allergen of Penicillium brevicompactum, which is known to be one of the major source of indoor fungal allergies. Pen b 26 was isolated and cloned into Escherichia coli as an N-terminus his-tagged fusion protein, which had a calculated molecular weight of 14.9 kDa while the native Pen b 26 was 11 kDa. The over-expressed fusion protein migrated at about 20 kDa on SDS-PAGE although its analysis by mass spectroscopy confirmed its calculated size. The IgE antibodies in the sera of >25% Penicillium -allergic individuals showed positive reaction to the purified fusion protein. Pen b 26 was also identified as a 60S ribosomal P1 phospho-protein. This invention includes a cDNA sequence from which the recombinant allergen was produced. |
| priorityDate | 2005-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 64.