| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fe135751dcf02df4fb4c62695adb4aaa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1ada37de67c4ede6a67e54f76e3f4484
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_12222865d4a804a148b466a063bf9995
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9e2deb56868cdc9824e0772eeef60b40 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6872
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70567
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4747 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-08 |
| filingDate |
2006-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_245571739d14ff6206588a242bc7314c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d037f77b45f4f9e1f4abbbbc01da661
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f894e3390401a00af8a133e39dba4762
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd3e7173858ef63000e20802f818837f |
| publicationDate |
2007-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2007054863-A1 |
| titleOfInvention |
Compounds that regulate apoptosis |
| abstract |
Compounds that modulate the function of anti-apoptotic proteins such as Bcl-2 and related Bcl-2 family members are identified. These compounds have the ability to convert the activity of Bcl-2-family member proteins from anti-apoptotic to pro-apoptotic. Methods for inducing or preventing apoptosis are described, together with methods for identifying molecules that induce or prevent apoptosis through interaction with Bcl-2-family members. Methods for treatment of proliferative diseases and neurodegenerative diseases using the modulators of Bcl-2 and related family members are also disclosed. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8034779-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114426573-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008154207-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015174144-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009048168-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8445441-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009118135-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11419843-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009012376-A1 |
| priorityDate |
2005-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |