Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aaaa80ab8f65d5c7c9fa7422cf51c754 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ebc6a4286c4c7ef3a3d96ccf785430c8 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-545 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-303 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-675 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-675 |
filingDate |
2004-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a17405c63c185fdff2b7ef43dc0ca930 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cdb5952d047b9a11cb7b0d49cb5d7aa9 |
publicationDate |
2007-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2007036809-A1 |
titleOfInvention |
Tolerance-induced targeted antibody production |
abstract |
The present invention provides methods for directing the immune response of an animal towards immunologically weak or rare antigens such as tumor antigens. The methods combine subtractive immunization with hyperimmunization and result in the controlled or directed production of target-specific antibodies, helper T cells (CD4 + -T lymphocytes) and cytotoxic T cells (CD8 + -T lymphocytes). Also provided by the present invention are untransformed and transformed cell lines, and growth media necessary to grow the untransformed cell line in a differentiated state. Monoclonal antibodies which react with different neoplastic cell lines and hybridomas producing such antibodies are also provided. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11266734-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015203582-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10736956-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110333346-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10179806-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9968670-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011027270-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2017275587-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8673314-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10564148-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10030072-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9175069-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9701723-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9849172-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10544207-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9708373-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10131695-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10137189-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10583188-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9371366-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9908930-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11254733-B2 |
priorityDate |
2003-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |