Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1a88050e8910c7b6a856c625b22537d8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e52e32131bf8eb9eb1387a9cb6772cc3 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-90 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-90 |
filingDate |
2006-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_abe4189172127944bffc1fd857b16b7b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_77d65ba0bd47a76ec35362222830fb40 |
publicationDate |
2007-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2007036718-A1 |
titleOfInvention |
Radiolabelled phenylethyl imidazole carboxylic acid ester derivatives |
abstract |
Halogenated carboxylic ester derivatives of phenylethyl imidazole, and their method of preparation are disclosed. Radio-halogenated forms of these compounds are ideally suited for positron-imaging of the adrenal glands, as it is known that these compounds demonstrate a selective and high rate of accumulation in the adrenals. The method of preparing these derivatives proceeds by the conversion of a stable, non-radioactive intermediate having trialkylstannyl leaving groups. These intermediates are efficiently converted to the corresponding halogenated forms by substitution of the trialkylstannyl group with the halogen or radiohalogen. |
priorityDate |
2003-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |