http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007032661-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4cdb1ef9fe36ae01e3729156a7103103 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-42 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-42 |
| filingDate | 2006-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af1c1d5da7379287756f6ad902df0b92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c9a506f06be569363214da0d74b36e6b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f70e0f30b41062d3315d145dd2047329 |
| publicationDate | 2007-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2007032661-A1 |
| titleOfInvention | Process for the preparation of intermediates of perindopril |
| abstract | A process for the preparation of (2S, 3aS, 7aS)perhydroindole-2-carboxylic acid is provided comprising (a) esterifying a cis-perhydroindole-2-carboxylic acid with a first alcohol of the formula ROH and a suitable free acid to provide the acid salt (AS) of Formula V: n n n(b) reacting the acid salt of Formula V with a first base to provide a compound of Formula VI: n n n(c) treating the product of step (b) with an L-tartaric containing acid in a second alcohol of the formula ROH to precipitate a compound of Formula VII: n n n(d) reacting the compound of Formula VII with a second base to provide a compound of Formula II n n(e) hydrolyzing the compound of Formula II to provide the (2S, 3aS, 7aS)perhydroindole-2-carboxylic acid. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005250706-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007255362-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023098640-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108752259-A |
| priorityDate | 2005-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 273.