http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007032647-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c3af615d245c5f9eff11b72a0474b56 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D223-28 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D223-18 |
| filingDate | 2004-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_489f776446d234d02e65cfeb357eb83d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d6210f91359c2d3abefa9e3dc1ff8dc |
| publicationDate | 2007-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2007032647-A1 |
| titleOfInvention | Novel process for preparation of 10-oxo-10, 11-dihydro-5h-dibenz [b,f] azepine-5-carbox- amide (oxcarbazepine) via intermediate, 10-methoxy-5h-debenz[b,f] azepine-5-carbonyl- chloride |
| abstract | A process for preparation of 10-oxo-10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide (oxcarbazepine) via intermediate 10-methoxy-5H-dibenz[b,f]azepine-5-carbonyl chloride, comprising the steps: a) Preparation of an intermediate 10-methoxy-5H-dibenz[b,f]azepine-5 carbonyl, chloride from 10-methoxyiminostillbene using bis (trichloromethyl) carbonate (BTC) with organic base such as aliphatic or aromatic tertiary amines in organic solvent; b) Conversion of the intermediate to 10-methoxy-5H-dibenz[b,f]azepine-5-carboxamide using ammonia in organic solvent; c) Formation of oxcarbazepine from step (b) using Bronsted acid in an organic solvent at a temperature between 25° C.-80° C., preferably at 50° C. to 70° C.; and d) Isolation of oxcarbazepine. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011065917-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007254033-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7722898-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7858779-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007149507-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8530647-B2 |
| priorityDate | 2004-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 195.