| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d1db9bc2a965bbfa4b5c9f3f33720d29
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf02a34442db2212dd8daa593a701f9c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ccf47503e02fe539b0a98a4d1f42586f |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-88 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 |
| filingDate |
2004-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bdb4a3ec24e587deb52f1809c0bd6b11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01e190bebbd248c4dc7a8093a7e06385
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_06c438848e6a262d01443b2d5306e397 |
| publicationDate |
2007-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2007032483-A1 |
| titleOfInvention |
Process for the production of mycophenolate mofetil |
| abstract |
The present invention relates to a new and economically attractive process for the production of mycophenolate mofetil in a high degree of pharmaceutically acceptable purity, which comprises the reaction of a reactive derivative of mycophenolic acid with 4-(2-hydroxyethyl)morpholine under acidic reaction conditions and the subsequent extraction of the pure mycophenolate mofetil through salt formation and release of the free base. A further aspect of the invention relates to the purification of mycophenolate mofetil by removing its by-products, in particular its dimeric by-products, by means of treatment with a primary or secondary amine. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008254520-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008009050-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005250952-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7683188-B2 |
| priorityDate |
2003-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |