| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_51909ddf381fce96476af0b58555fe21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_32f565d52744d515e64188fcd4cfe295
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f6dc875920b3245b15d1846dac13513c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d9865da1ad7d772bc30d195119f481f2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1db825b7ae0aa30215e2067dee758468
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fd9d5b8e54d5381f8486cfaa4d77e01f |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-605 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-10 |
| filingDate |
2006-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_456df27904f22296ae6bc838970d4a2d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_44cc3ce2a3539351ce3c344f8211ad98
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd44e2210becdac6578e9098d266d267
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_77f5db22e149655ea37319694ff0c7bc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cdbc8655b5f79e65aef86481a0fa62c9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f79cb92e58d72eadaef13ce110b1c4c5 |
| publicationDate |
2007-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2007021346-A1 |
| titleOfInvention |
N-terminally modified GLP-1 receptor modulators |
| abstract |
The subject matter described herein provides novel human glucagon-like peptide-1 (GLP-1) receptor modulators that have biological activity similar or superior to native GLP-1 peptide and thus are useful for the treatment or prevention of diseases or disorders associated with GLP activity. The described compounds include chemically modified peptides that not only stimulate insulin secretion in type II diabetics, but also produce other beneficial insulinotropic responses. These synthetic peptide GLP-1 receptor modulators exhibit increased stability to proteolytic cleavage making them ideal therapeutic candidates for oral or parenteral administration. The disclosed and claimed peptides show desirable pharmacokinetic properties and desirable potency in efficacy models of diabetes. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018106782-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7960349-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017161318-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011048614-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019060634-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108697767-A |
| priorityDate |
2005-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |