http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007015822-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_50bac0a70ac616da2a97686d5d0fa2c6 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-727 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-726 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-737 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-335 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-355 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-355 |
filingDate | 2006-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_828c2817ae908f3f8bf5e0cc443e6254 |
publicationDate | 2007-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2007015822-A1 |
titleOfInvention | Methods for selectively treating COX-2 mediated disorders by administering gamma-tocopherol |
abstract | The present invention is based upon the novel observation of the COX-II-specific inhibitory activity of gamma-tocopherol and that by combining gamma-tocopherol with precursors of connective tissue constituents, injured or degenerated connective tissue, especially of articulated joints of animal patients, may be repaired. The method of the invention for treating a inflammatory disorder of a joint comprises administering to the mammal a pharmaceutical composition comprising an amount of gamma-tocopherol effective in selectively inhibiting cyclooxygenase-2 and at least one compound that elevates the production of a component of connective tissue in an amount effective for the promotion of connective tissue formation. The invention also provides pharmaceutical or veterinary compositions comprising a tocopherol preparation having at least 50% w/w gamma-tocopherol or a derivative thereof and in an amount effective for selectively inhibiting cyclooxygenase-2 in the recipient mammal and at least one compound that elevates the production of a component of connective tissue. |
priorityDate | 2005-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 250.