| abstract |
The present invention provides a pharmaceutical composition for use as an NPY Y5 receptor antagonist comprising a compound of the formula (I): n n nwherein R 1 is lower alkyl, cycloalkyl or the like, n nR 2 is hydrogen, lower alkyl or the like, nn is 1 or 2, X is lower alkylene, lower alkenylene, arylene, cycloalkylene or the like, n nY is CONR 7 , CSNR 7 , NR 7 CO, NR 7 CS or the like, n nZ is lower alkyl, optionally substituted carbocyclyl, optionally substituted heterocyclyl or the like and R 7 is hydrogen or lower alkyl, nprodrug, pharmaceutically acceptable salt or solvate thereof |