http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007015715-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_08e518c9469c0d8aed8634dc54203812 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-282 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-043 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-282 |
| filingDate | 2006-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_538b9590a6038a13458eff698fc81b6a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5087f08670f065c007a9df60ccebd1b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0bab7dd570b60d7936ff7ae1956c8555 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8651cdada7912db40027ac6f9ddac651 |
| publicationDate | 2007-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2007015715-A1 |
| titleOfInvention | Method of treating cancer and neuropathic complications induced by chemotherapeutic agents using selective Bradykinin B1 receptor antagonists |
| abstract | The present invention relates to a method for the use of a bradykinin B1 receptor antagonist of formula I: n nX—CO-Aaa 0 -Aaa 1 -Aaa 2 -Aaa 3 -Gly-α(Me)Phe-Ser-D-βNal-Aaa 8 -OH (I)nor a pharmaceutically acceptable salt or hydrate thereof wherein: n X is C n H 2n+1 or C i H 2i —C 6 H 5 , where n is an integer from 1 to 3, and i is an integer from 0 to 3; Aaa 0 is Lys, Orn or Cit; Aaa 1 is Arg or Cit, and preferably Arg; Aaa 2 is Oic, Hyp or Pro, and preferably Oic; Aaa 3 is Pro or Oic, and preferably Pro; and Aaa 8 is Ile, Leu, Nle, and preferably Ile, for the treatment of metastases, cancers and/or chemotherapy-induced neuropathies, comprising the administration of said compound to a patient in need of such treatment. The present invention also relates to compositions containing such antagonists and the uses thereof. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2018524401-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7091241-B2 |
| priorityDate | 2004-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 125.