| abstract |
A perfusion system for the extracorporeal preservation of vitality or regeneration of organs, limbs or tissue lobes for use in transplant surgery, extracorporeal support of the liver, or for biochemical or pharmacological study of isolated organs. The system comprises an organ perfusion chamber filled with dialysate as the storage fluid and equipped with a temperature control device. An impermeable protective cover in the organ perfusion chamber is surrounded by the storage fluid. The cover receives the isolated organ and protects it from the storage fluid. The circulation system for maintaining vitality of the isolated organ includes a perfusate circulation system, an oxygenator, a dialyzer, and a dialysate circulation system. The perfusate circulation system comprises one or two pumps and two valves for independently dosing the perfusate partial flows and setting the mixing ratio, and not more than two reservoirs for collecting the perfusate. |