| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b095f2ffe7162385d7a1fac05ef02c07
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4bfb57f2d9d8c6a78e97a49cff650b8a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d1c6b7e820fd0782a6664e6de7f9fa23 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-111 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1137
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y301-04004 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N43-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K-
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 |
| filingDate |
2004-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ace2acbcd3838e6043e1c850000c3ff
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_41d0423ba360278ceacdee5e64b26e63
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0fac0ce659b489362206a0c0d45ce0d2 |
| publicationDate |
2007-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2007004657-A1 |
| titleOfInvention |
Diagnosis and treatment of kidney fibrosis and other fibrotic diseases |
| abstract |
The present invention provides methods of treatment of fibrosis by identification and isolation of polynucleotide sequences, the expression of which is altered in fibrosis. The present invention also relates to the use of these isolated polynucleotides and the polypeptides encoded thereby as probes for diagnosis, for screening of treatment modalities and as targets for modulation in kidney fibrosis and in other fibrotic conditions, including ocular scarring and cataract. In particular, the present invention provides methods, compounds and pharmaceutical compositions for the treatment of fibrosis in general, and kidney fibrosis and related pathologies and ocular scarring and cataract in particular. Novel pharmaceutical compositions comprising oligonucleotides or antibodies are also provided. |
| priorityDate |
2003-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |