Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_86a533d313f31f6037d84e96156b0226 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2400-0487 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-0268 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0816 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2400-086 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2400-0418 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H01J49-165 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-502746 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H01J49-0018 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01L3-00 |
filingDate |
2005-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_93fc55c225fb8036cdaf63f7e5a4871c |
publicationDate |
2006-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2006285999-A1 |
titleOfInvention |
Apparatus and method for coupling microfluidic systems with electrospray ionization mass spectrometry utilizing a hydrodynamic flow restrictor |
abstract |
A microfluidic device is disclosed wherein a hydrodynamic flow restrictor is positioned in a main channel; a make-up flow channel engages the main channel at a position between the hydrodynamic flow restrictor and an output channel. The hydrodynamic flow restrictor substantially negates a hydrodynamic backpressure in the main channel to the extent that low electroosmotic flow may be utilized in the main channel. Further, a method is disclosed wherein a sample is delivered to the main channel and low EOF drives the sample through the main channel. The method comprises positioning a hydrodynamic flow restrictor in the main channel and delivering a make-up solution via hydrodynamic flow to the main channel at a position between a hydrodynamic flow restrictor and the output channel. The hydrodynamic flow restrictor substantially negates a hydrodynamic backpressure in the main channel to the extent that low electroosmotic flow may be utilized in the main channel. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015076342-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10861689-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9196468-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015340219-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2014305801-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101817495-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9816924-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104698064-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114308153-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9818594-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023122232-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9927396-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2018130650-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2463549-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113327836-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2463549-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10312070-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10134576-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105647789-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015050960-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2022208538-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2017025263-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9502225-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109682902-A |
priorityDate |
2005-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |