Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_52a2a1320fa5f4ca57783a8119c610d4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2f24087e3bbe448a08e92a85586ef540 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6420a699807f548ac2ca71eda940d411 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-325 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-05 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0275 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8509 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-567 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B30-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4745 |
filingDate |
2006-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f4e16e288208be42dcdbdf68aaa4615c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_875a7ce11bad3961e4eecb377f3eb590 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd4973dadd9a44485b9d22af58de5912 |
publicationDate |
2006-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2006282909-A1 |
titleOfInvention |
Methods and compositions for therapeutic intervention in cardiac hypertrophy |
abstract |
The present invention relates to cardiac hypertrophy. More particularly, the present invention defines the molecular events linking calcium stimulation to cardiac hypertrophy. More specifically, the present invention shows that Ca++ stimulation of the hypertrophic response is mediated through NF-AT3. Thus, the present invention provides methods of treating cardiac hypertrophy as well as transgenic constructs for preparing transgenic animals. Further provided are methods of using the transgenic animals of the present invention, or cells isolated therefrom, for the detection of compounds having therapeutic activity toward cardiac hypertrophy. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015157610-A1 |
priorityDate |
1998-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |