Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9dddca2a23582effb9c5250ea450c304 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6429 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-21005 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-06 |
filingDate |
2003-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c529f3f2d4dace72663d25c482a8c041 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67448b2c8300967757f80b3563aca5d3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f232df131d6c1366f576341592ebbf8d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aaa1a18fba66f640d6ea6ea050d948ce http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d3a2b860b014bc5c92be18e51f8292a6 |
publicationDate |
2006-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2006281147-A1 |
titleOfInvention |
Thrombin-like recombinant baxtroxobin expressed by pichia sp.and production method thereof |
abstract |
A recombinant thrombin-like enzyme batroxobin expressed by yeast, a production method thereof, and use of the batroxobin as a hemostatic agent or antithrombotic agent is disclosed. In order to express recombinant thrombin-like enzyme, an expression vector is prepared by inserting cDNA encoding the enzyme, the transformed cell is prepared by introducing the expression vector into the cell, the transformed cell then is incubated and the recombinant thrombin-like enzyme is obtained from the cell. The recombinant thrombin-like enzyme may be usefully used as a hemostatic agent because the enzyme effectively decrease bleeding time and blood coagulation time and does not affect various blood coagulation factors. The recombinant thrombin-like enzyme is also useful for a hemostatic agent or antithrombotic agent comprising the recombinant thrombin-like enzyme as an active component |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008119203-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010047229-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100981294-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7939067-B2 |
priorityDate |
2003-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |