Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9d1b4d10273f76050182e2c281086dfa http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dbee2f7d615857d32fd5b61badae6df0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_15f1c077c48b4756eaf60439bb7f7193 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1051 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y204-01212 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-10 |
filingDate |
2006-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_305c378f29d5b8095e5b8f81f9367073 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc5d7f775b79384f545af57f52b64818 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5672c247f1a9031007592e54314fcbf2 |
publicationDate |
2006-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2006276636-A1 |
titleOfInvention |
Hyaluronate synthase gene and uses thereof |
abstract |
Disclosed are DNA sequences encoding hyaluronic acid synthase that are employed to construct recombinant cells useful in the production of hyaluronata synthase and hyaluronic acid (HA). In preferred aspects, chromosomal DNA encoding the HA synthase gene, hasA, was cloned from a Streptococcus pyoganas genomic library. These vectors were used to transform host cells such as E. coli and acapsular Streptococci to produce hyaluronic acid. Resultant transformants were screened to identify colonies which have incorporated HA synthase DNA in a form that is being actively transcribed into the corresponding HA synthase enzyme. These colonies were selected and employed in the production of hyaluronic acid. |
priorityDate |
1994-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |