Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fdad00677b9268c26e005a9e03a7b9dd |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-4703 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5058 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5014 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-08 |
filingDate |
2006-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ab09b1757c0d30e8f9b200d8a8ce69c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c0c71834b1ebb7c0988103d7bc37f8f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9eb844eb255fe0e84e54e2ea4194b6d8 |
publicationDate |
2006-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2006275275-A1 |
titleOfInvention |
Cells and methods for estimation of effects on neurological dysfunction |
abstract |
The invention provides neuron-derived cells obtained by transfecting a receptor-expressing nucleic acid having an aryl hydrocarbon receptor gene, wherein outgrowth of neurites is not observed without adding a substance for the aryl hydrocarbon receptor, and outgrowth of neurites is observed by adding the substance for the aryl hydrocarbon receptor. The invention also provides a method for determining the presence of neurotoxicity of a test substance, a method for acquiring a marker for determining the presence of neurotoxicity of the test substance, a method for acquiring a marker for neurological dysfunction, and a method for determining the effect of the test substance on neurological dysfunction using such cells. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7413898-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7811760-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009253167-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008003596-A1 |
priorityDate |
2005-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |