| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8adf1aa119f2fa8c92dc31e5ef07b387 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C271-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C271-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D263-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-06 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-02 |
| filingDate |
2006-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2242e86a9c27a62f2591094d3030f484 |
| publicationDate |
2006-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2006264643-A1 |
| titleOfInvention |
One Pot Synthesis of 2-Oxazolidinone Derivatives |
| abstract |
The present invention provides an improved process for preparing (S)-4{[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]methyl}-2-oxazolidinone which comprises: a) forming a carbamate of formula (III), from methyl 4-nitro-(L)-phenylalaninate hydrochloride; b) reducing the compound of formula (III) to give the compound of formula (IV); c) reducing the methyl ester grouping in the compound of formula (IV) to give the compound of formula (V); d) ring closure of the compound of formula (V) to give the compound of formula (VI); e) diazonium salt formation from the compound of formula (VI) followed by reduction to give the compound of formula (VII); f) Fischer reaction of the compound of formula (VII) to give (S)-4{[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]methyl}2-oxazolidino |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009079547-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008057027-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8372399-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008057053-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8636995-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008058922-A1 |
| priorityDate |
1995-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |