| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9db87611f78c117e6b3cda7229552c88 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6927
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-585
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-23 |
| filingDate |
2006-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1ab3ded5728eb509e33dd578bd0d1d2b |
| publicationDate |
2006-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2006210641-A1 |
| titleOfInvention |
Absorbable microparticles |
| abstract |
This invention pertains to a sustained release complex of one or more peptides, one or more proteins or a combination thereof immobilized on an absorbable polymer microparticle optionally having an absorbable polymer coating. The microparticle complex of this invention comprises a peptide(s) and/or protein(s) which have at least one amino group and/or at least one carboxyl group per molecule and a solid absorbable polyester microparticle having surface and subsurface carboxylic group or amino groups in sufficient amounts to bind the peptide(s) and/or protein(s) so that the immobilized peptide(s) or protein(s) represent 0.1% to 30% of the total mass of the microparticle complex. The microparticle complex with immobilized peptide(s) and/or protein(s) are optionally further encased individually or in groups with an absorbable polymer to control, further, the release of the immobilized peptide(s) and/or protein(s). To control the release of the immobilized peptide(s) and/or protein(s) even further, the encased microparticles can be incorporated into a composition with an absorbable gel-forming liquid that transforms to a flexible gel or semi-solid upon contacting water in the biologic environment. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10308699-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10669230-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10227380-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9845287-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10953103-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9957299-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017077066-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10213477-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9096684-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11291636-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9522947-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10253067-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10471120-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10301351-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10202431-B2 |
| priorityDate |
1998-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |