| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a7f82940e47ba7a1188f8e2ffca55e0f |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-415 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-473
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 |
| filingDate |
2005-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1801877cd2a7a672601b95eee85bac80
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d9b81b5f0e7e52ac7fc90b6b42eb1e7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c15655b4fabf52f3bf44c7fc0a61269
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_05bd60f739ce048e73f289d192575398 |
| publicationDate |
2006-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2006205755-A1 |
| titleOfInvention |
Novel farnesyl protein transferase inhibitors as antitumor agents |
| abstract |
Disclosed are novel tricyclic compounds of the formula: n nand the pharmaceutically acceptable salts thereof. Y is C or CH. When Y is C then Z is not present and the optional bond from Y to the C-11 carbon of the tricyclic nucleus is present. When Y is CH then Z is present and Z is H or —OH. The compounds are useful for inhibiting farnesyl protein transferase. Also disclosed are pharmaceutical compositions comprising the compounds of formula 1.0. Also disclosed are methods of treating cancer using the compounds of formula 1.0. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7557107-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005059672-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007213340-A1 |
| priorityDate |
2004-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |