Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9153d55db39d0cd2b08ce8e88dd65571 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d0d766bd1ea93c4289a85b77b878189c |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-73 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 |
filingDate |
2005-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e0569f35be18cd578af7af32060c3052 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_299930a95eb506c9e15f25b859c7f0aa |
publicationDate |
2006-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2006199780-A1 |
titleOfInvention |
Methods for modulating T cell survival by modulating bcl-XL protein level |
abstract |
Methods for protecting a T cell from cell death are described. The methods involve contacting the T cell with an agent which augments the bcl-X L protein level in the T cell such that it is protected from cell death. The invention further pertains to methods for increasing the susceptibility of a T cell to cell death, comprising contacting the T cell with at least one agent which decreases bcl-X L protein level in the T cell. Both in vivo and in vitro methods are described. |
priorityDate |
2000-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |