| abstract |
The present invention relates to new compounds of formula I, Wherein Y is NR 4 CONR 4 , NR 4 CO, or NR 4 ; R 1 is nitro or COR 5 ; R 2 is hydrogen or NH 2 ; R 3 is C 1-6 alkyl or C 0-6 akylaryl wherein C 0-6 alkylaryl may be substituted by A; R 4 is hydrogen; R 5 is C 1-6 alkyl; A is independently selected from halo, OR 6 and C 1-6 alkyl; R 6 is C 1-6 alkyl; provided that the compound is not N-(4-Methoxybenzyl)-N′-(5-nitro-1,3-thiazol-2-yl)urea as a free base or a salt thereof as well as a process for their preparation, pharmaceutical formulations containing said therapeutically active compounds and to the use of said active compounds in therapy. |