http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006183696-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4cb501aaad6e51ce0549e119b986c76e |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7052 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J17-00 |
filingDate | 2006-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78a6ca9648f36adeac0554fbc92ff1cb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7491188ac4a6db8f68c215dd3728f64d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_894c58c4f77ca716af1e66d67a6467f1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_60961e99a8649d5c9a84212f78904957 |
publicationDate | 2006-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2006183696-A1 |
titleOfInvention | Use of immune cell specific conjugates for treatment of inflammatory diseases of gastrointestinal tract |
abstract | The present invention is directed to methods for the prevention and treatment of inflammatory diseases, disorders, and conditions of gastrointestinal tract by administering to a patient in need of such treatment, conjugate compounds of Formula VII having low oral-bioavailability, or pharmaceutically acceptable salts, prodrugs, or solvate thereof: n nwherein M represents a macrolide subunit possessing the property of accumulation in inflammatory cells, T represents an anti-inflammatory subunit that can be a steroid or nonsteroid (nonsteroidal moiety) derived from a non-steroid drug with anti-inflammatory, analgesic and/or antipyretic activity (NSAID) and L represents a linker covalently linking M and T. The present disclosure is also directed to pharmaceutical compositions containing conjugate compounds of Formula VII having low oral-bioavailability. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014166503-A1 |
priorityDate | 2004-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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