http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006173219-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_795a4d2530ef8564bb8da68b19379550 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B41-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C47-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-513 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-516 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-45 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F1-02 |
filingDate | 2005-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7413213b765b42a7d546ea4512d5473 |
publicationDate | 2006-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2006173219-A1 |
titleOfInvention | Protective groups for crossed aldol condensations |
abstract | A process for protecting aldehydes and ketones in crossed aldol condensations where both aldols possess alpha-carbon hydrogens, comprising protecting the target aldol by forming an acetal or imine with an alcohol, glycol or primary amine which may contain electron-withdrawing groups, adding a base of sufficient strength to abstract a proton from the alpha-carbon of the acetal or imine and adding the second aldol to form the salt of the saturated hydroxy addition compound, thereby minimizing by-products, waste and separation difficulties, then forming the unsaturated addition compound and decomposing the acetal or imine with dilute acid. This process having the advantage that a ketone may be added to a protected aldehyde target to produce an aldehyde as a product which was not previously possible. |
priorityDate | 2005-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 75.