| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a62a67c40446a242868463a1b6f4c49c |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C315-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C315-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C319-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C335-32 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C317-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-60 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C315-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C315-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-165
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C335-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-39
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C319-14 |
| filingDate |
2004-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5c315232f7868691fd40af15fc304ae |
| publicationDate |
2006-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2006160903-A1 |
| titleOfInvention |
Process for preparing benzhydrylthioacetamide |
| abstract |
The present invention is directed to an improved process for preparing modafinil wherein benzhydrylthioacetamide is prepared in high yield and purity by the reaction of a haloacetamide with the reaction product of thiourea and benzhydrol in aqueous solution. The reaction employing the haloacetamide is conducted in a solvent comprising water and an organic solvent such as dimethylformamide having dissolved therein a basic salt such as potassium carbonate. The resulting benzhydrylthioacetamide can be oxidized to provide the pharmaceutical modafinil. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007293702-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008031939-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7960586-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009048464-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8048222-B2 |
| priorityDate |
2003-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |