http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006148020-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_734fe40dba3c7b80171f74b2c05913ce |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-063 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-28 |
| filingDate | 2003-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d466bca0f33145be31bed6dd9e3c624c |
| publicationDate | 2006-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2006148020-A1 |
| titleOfInvention | Inhibitors of gst a3-3 and gst a1-1 for the treatment of cancer |
| abstract | The present invention relates to a novel drug target, glutathione transferase (GST), preferably GST A3-3, as target for treatment of cancer and other diseases responsive to inhibition of steroid hormone production. The present invention also relates to a method for screening of compounds or drug candidates that modulate, preferably inhibit, the activity of GST, in which method GST is used as a drug target. The invention further relates to the use of inhibitors of GST A3-3 for production of a drug for treatment of steroid hormone dependent diseases, such as for treatment of cancer, preferably prostate cancer or breast cancer. The present invention also relates to a method for treating cancer or steroid hormone dependent diseases, comprising administering, e.g., a non-steroidal compound that modulates the tissue concentration of GST A3-3 or inhibits the enzymatic activity of GST A3-3, to a human in need of such a treatment. |
| priorityDate | 2002-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 129.