| abstract |
The invention relates to methods and compositions for the treatment and diagnosis of body weight disorders, including, but not limited to, obesity, overweight, anorexia, cachexia, insulin resistance, and diabetes. The invention further provides methods for identifying a compound capable of treating a body weight disorder. In addition, the invention provides a method for treating a subject having a body weight disorder characterized by aberrant 58128 polypeptide activity or aberrant 58128 nucleic acid expression. In another aspect, the invention provides methods for modulating 58128 polypeptide activity or 58128 expression in a subject. |