| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fc749f1664b12bdc8272dffee7ce421f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c9870a89c7ac609c4021c562dea29c9f |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1688
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-145
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4745
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D281-18 |
| filingDate |
2005-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_196f055a385cc725348d42ef2cc5442c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e25fe31074b6e5723d2c8bff9e2ecc9 |
| publicationDate |
2006-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2006142564-A1 |
| titleOfInvention |
Methods of preparing pimecrolimus |
| abstract |
The present invention provides a process for the preparation of pimecrolimus from ascomycin in which ascomycin is reacted with a conversion reagent that converts ascomycin to its activated derivative at C-32. The activated ascomycin is then reacted with chloride ion. The process of the invention requires fewer process steps than prior art processes, and does not require the protection of the ascomycin C-24 hydroxyl group or the purification of the activated ascomycin derivative. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9878328-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009082386-A1 |
| priorityDate |
2004-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |