| abstract |
The present invention provides pharmaceutical agents for preventing headaches, especially headaches associated with migraine, tension headaches, and chronic daily headaches. The prophylactic treatments in accordance with the present invention can reduce the frequency of headaches, such as migraine attacks, as well as reducing their severity and duration when they do occur. The pharmaceutical agents can comprise a combination of a cyclooxygenase-3 inhibitor and beta-adrenergic receptor antagonist in amounts which are effective to achieve the desired purpose of preventing headaches. In addition, the present invention provides compositions and methods for treating headaches, comprising administering a cyclooxygenase-3 inhibitor. |