Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a6d36bcd4ce1b47748962c4f4d1389db http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_748fc7aa897ab482cc8b49c7337deaf1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dbcb7f89b6eb561dd08876e88b6b9587 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K6-69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K6-20 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K6-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K6-083 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-81 |
filingDate |
2003-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5cc08cb391a72c2f26fdfab8cfad0a18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0cab09ee2d2a1cfeca922fa78198ffbc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d4faf9fd7e9b4fe6b27b9b703adcef2b |
publicationDate |
2006-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2006134012-A1 |
titleOfInvention |
Temporary pharmacologically-inactive dental coating for the in situ protection of dental therapeutic agents from saliva and abrasion from chewing |
abstract |
Topical application of a pharmacologically-inactive, inert polymeric solution to teeth affords a temporary, protective barrier for pharmacologically-active compounds that have been previously applied topically to the tooth surfaces for caries reduction. In a method of use, an aqueous dispersion polymethylmethacrylate (PMMA) and a suitable plasticizer are applied topically to the tooth surface immediately after the topical application of chlorhexidine or fluoride. The inert coating thus formed is distinct from any pharmacologically-active substance, and remains on the tooth surface until abraded by the chewing of hard foods. In a composition of matter, the solution contains ammonio methacrylate copolymer, type B USP/NF of between 20% and 35% w/w; triethyl citrate USP/NF of between 1% and 10% w/w; and purified water of between 60% and 70% w/w. The ammonio methacrylate copolymer is preferably EUDRAGIT RS 30 D brand available form Rohm GmbH. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9107838-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113382769-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021042325-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019172884-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3922311-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013163196-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2705825-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014037337-A1 |
priorityDate |
2002-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |