Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e047ad7efe4a6f4efb03d8640d5be732 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b40a9b989ae663bac0c1cd570178d998 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c46b39d877982973f8a302a76218960a |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-2408 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-24 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-02 |
filingDate |
2003-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_308d7ac6f479ee8e9d3c5d1e4b3a0c6b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7087d9323b1ac2c46d577d7a07fc0ca4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3510c07e7ab9218c98bdb9a99cac23a |
publicationDate |
2006-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2006128951-A1 |
titleOfInvention |
Process for preparing phosphorodiamidites |
abstract |
A method of phosphorodiamidite production comprising the steps of reacting a phosphorus trihalide with a dialkyl amine in a polar solvent to form an intermediate compound. This intermediate compound is then subsequently reacted with an hydroxylalkyl compound and a dialkyl amine in the presence of a non-polar co-solvent. Following filtration to remove the solid by-product the two solvents form separate layers. This is advantageous as the upper, non-polar solvent, layer contains the high-purity phosphorodiamidite product. |
priorityDate |
2002-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |