Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_acf264216fc883cdc34e5282c7a0a5b9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cade9b12fe98cf765be254b4b85ffa0f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6106eb8b8d5332e90da52da0afadee0c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b361315b6f869221c7bf79dd2a2ff396 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_891613e65131dff24154bafe9e3da9fb |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-695 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-06 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-695 |
filingDate |
2005-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94121951c01128a0abf519ee590fee32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_72f179f34e2e81d71bcdf3b29bf15bfd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de0d63e5a488cef877e7d9f0aa83dea3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b3c2fa1ae1812e91094339455f4a8fe6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e60e98abd5c9a92c6cc6d851fe2d4ce |
publicationDate |
2006-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2006128620-A1 |
titleOfInvention |
Adrenocorticotropic hormone analogs and related methods |
abstract |
ACTH analog compounds of the present invention include compounds comprising an ACTH peptide sequence with one or more structural modifications that can have one or more of the following preferred ACTH analog biological functions: (1) reduction of corticosteroid secretion by adrenal membrane in the presence of the ACTH analog compared to unmodified ACTH, (2) reduction of corticosteroid secretion by adrenal membrane in the presence of endogenous ACTH and (3) increased MC-2R binding affinity with reduced activation of the MC-2R receptor compared to unmodified ACTH binding to the MC-2R melanocortin. The ACTH analog compounds of the present invention are therefore useful for treatment or prevention of diseases and disorders related to ACTH, ACTH receptors or corticosteroid secretion, such as premature labor and Cushing's Disease. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10550180-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2020055899-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11534481-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11673917-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018118115-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11427631-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9688754-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11338018-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11419919-B1 |
priorityDate |
2004-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |