http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006115469-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_916075766043ce900399a4c2eee9f054 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6491 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-4886 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-48 |
| filingDate | 2004-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b0025ea11dc88c5e2d9a38825f81bd63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b7a03eb21323e8131e1ede6fa9b36f97 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6aa8ab0f6fc6790c9c8ec1cb49e830ce http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7e71fb77f59ad59c8c3dc4aa53a377fe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76490c468c04babe94e0b73a64be1da9 |
| publicationDate | 2006-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2006115469-A1 |
| titleOfInvention | Interstitial collagenase molecular motor |
| abstract | A novel interstitial collagenase is disclosed which acts as an ATP-independent molecular motor driven by the proteolysis of substrate collagen. Also disclosed is a method of reacting interstitial collagenase with a collagen fibril to encounter multiple cleavage sites without substantial dissociation of said interstitial collagenase and thereby act as a molecular motor driven by the proteolysis of substrate collagen. The invention thus is useful as a research tool in the tissue remodeling and cell-matrix interaction. The invention also has significant utility in the screening and development of inhibitors of interstitial collagenase and as a research tool for evaluating the activity and effect of drug candidates. |
| priorityDate | 2004-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 75.