http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006105431-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_15f1c077c48b4756eaf60439bb7f7193 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1051 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-28 |
filingDate | 2005-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_692665e2d45a4880f7d6fc1111211d0e |
publicationDate | 2006-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2006105431-A1 |
titleOfInvention | Polymer grafting by polysaccharide synthases using artificial sugar acceptors |
abstract | The present invention relates to methodology for polymer grafting by a polysaccharide synthase and, more particularly, polymer grafting using the glycosaminoglycan synthases from Pasteurella multocida . The methodology of the present invention includes providing an enzymatically active glycosaminoglycan synthase enzyme from Pasteurella multocida , providing a synthetic, artificial acceptor for the glycosaminoglycan synthase enzyme; combining the synthetic, artificial acceptor with the glycosaminoglycan synthase enzyme within a reaction medium, wherein the reaction medium contains at least one sugar precursor selected from the group consisting of UDP-GlcA, UDP-GlcNAc, UDP-GalNAc, and reacting the glycosaminoglycan synthase enzyme with the synthetic, artificial acceptor to produce an oligosaccharide or polysaccharide polymer. The glycosaminoglycan synthase enzyme may be hyaluronan synthase, chondroitin synthase, or heparosan synthase from P. multocida , and the oligosaccharide or polysaccharide polymer may be hyaluronic acid (hyaluronan), chondroitin, heparosan, or combinations thereof. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9175293-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8697398-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104388499-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7604973-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007298461-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7504246-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007087416-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8735102-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008130373-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9603945-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9925209-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2341941-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9687559-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2341941-A2 |
priorityDate | 1998-11-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 318.