| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_14bb393e0286be34567d92cd8e890008
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_050ceb4f07cc974b737253dcb6e533af
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a3c51285aa517a4f0d0d52f7c8f27069
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b9ef0486ba15cbd1b3ac969998881aaa |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-56 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-56 |
| filingDate |
2002-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b3e2d656d58a9ef69d71aa1a0eb042cb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_906a810d93126eb9bd2e3b8eb4ec9484
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9a82c31f32b0e1781a380160ef3d9e2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1de8dd7a1433472d930b1ce653246b2d |
| publicationDate |
2006-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2006100130-A9 |
| titleOfInvention |
Catalysis of the cis/trans-isomerisation of secondary amide peptide compounds |
| abstract |
The present invention is based on the finding that the cis/trans isomerisation of secondary amide peptide bonds in oligo- and polypeptides can be catalytically promoted. This catalysis is effected by enzymes which are hereinafter called “secondary amide peptide bond cis/trans isomerases (APIases). It can be assumed that the APIase activity plays a central role in a number of pathophysiological processes. Thus, the invention relates to pharmaceutical compositions comprising substances which inhibit APIase activity. |
| priorityDate |
2001-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |