| abstract |
The invention concerns a method for preparing an isolated extracellular matrix, secreted by tumor cells, in particular epitheliomatous cells, methods for tumor cell culture using such a matrix, the use of such a matrix for producing a tumor cell line as well as novel tumor cell lines obtained by said method. The invention also concerns a method for selecting a compound capable of inhibiting the growth and/or proliferation of tumor cells, the use of said compounds as medicine for cancer treatment as well as a diagnosis or prognosis method in vitro by chromosomal analysis using said matrices. The invention further concerns a reactor or a kit for cell culture comprising such an extracellular matrix. |