Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ffd4c098f036588e6b92f634909a6896 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-136 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18 |
filingDate |
2003-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1e6be1da8abfb965dd95653ff9a3788b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6155793e363b5bbf9981703914e83e31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ad3752128c976f649baedf31ed399c7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1459d51994d6df4ab92afba2e3614fe |
publicationDate |
2006-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2006099585-A1 |
titleOfInvention |
Diagnostic and therapeutic use of cyp11a1 for neurodegenerative diseases |
abstract |
The present invention discloses the differential expression of the CYP11A1 gene in specific brain regions of Alzheimer's disease patients. Based on this finding, this invention provides a method for diagnosing or prognosticating a neurodegenerative disease, in particular Alzheimer's disease in a subject, or for determining whether a subject is at increased risk of developing such a disease. Furthermore, this invention provides therapeutic and prophylactic methods for treating or preventing Alzheimer's disease and related neurodegenerative disorders using the CYP11A1 gene and gene products. A method of screening for modulating agents of neurodegenerative diseases is also disclosed. |
priorityDate |
2002-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |