| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a40c39fa424236fb51b9fde9707ee78 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6842
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5008
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5011 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 |
| filingDate |
2005-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba6339db96e0c565cb43f85ac2da8e7e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f1cc07e7c898c5b022a7a83a3416578
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae2038b5827b06f00ba18796180b0d08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7dbe65f879a50302dc7b2811e85c4313
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3b0f429a6bcf7e8b2c58023899ca985 |
| publicationDate |
2006-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2006088888-A1 |
| titleOfInvention |
Methods of identifying inhibitors of GADD45 polypeptide activity, and inhibitors of such activity |
| abstract |
The present invention is directed to novel methods for assaying for modulators of GADD45 polypeptide activity. The invention also provides means to sensitize a proliferating cell to a DNA base-damaging agent by administration of novel inhibitors of GADD45 polypeptide activity. The invention further provides polypeptides which interfere with the ability of Cdc2/cyclin B1 complexes to cause a pause at the G2/M stage of the cell cycle in response to GADD45, and nucleic acids which encode such polypeptides. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006280683-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2922865-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7438892-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016503425-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018053037-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11780895-B2 |
| priorityDate |
1999-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |