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filingDate 2004-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2006-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2006088556-A1
titleOfInvention Topical formulation and use of buspirone
abstract A liquid or semi-solid topical formulation of buspirone, when applied to human epidermis in vitro (following methods defined herein), results in a transepidermal flux rate of buspirone (individual or mean data) in one or more of the following ranges: 0.1 to 1.1 μg/cm 2 /hour as assessed over 5 hours following application; 0.09 to 0.60 μg/cm 2 /hour as assessed over 13 hours following application; 0.09 to 0.48 μg/cm 2 /hour as assessed over 24 hours following application; 0.08 to 0.46 μg/cm 2 /hour as assessed over 30 hours following application; and 0.08 to 0.39 μg/cm 2 /hour as assessed over 48 hours following application. Buspirone is useful for the manufacture of a topical medicament for use in the treatment of pruritus or an immune-related skin disease.
priorityDate 2003-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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